Impact of Managed Therapy on Adherence to Medications Used to Treat Multiple Sclerosis and Related Comorbid Conditions
Results: Mean proportion of days covered rates improved significantly in the group managed for at least 6 months compared with those who were less managed. Positive screenings for fatigue and depression reduced adherence in the less-managed group but not in patients with longer participation in the program.
Conclusions: Overall, the CCMS program significantly increased adherence to MS medications. This improved adherence was not negatively impacted by positive screenings for fatigue and depression.